Neural Modulation

Our lab explores electrical neuromodulation: a collection of therapies in which electrical stimulation modulates neural tissue activity to alleviate neurological symptoms. While some of these therapies are performed non-invasively, others require chronic implantation of an electrical stimulator -- over a million people are living with embedded electric circuits that regularly stimulate their brain or spinal cord! Though these interventions work quite well in some patients, clinicians and scientists have a very incomplete picture of how or in whom they will alleviate symptoms. We aim to improve and expand these therapies by identifying optimal anatomical targets, understanding their behavioral and physiological responses, leveraging neural feedback to assess their efficacy, and building devices to make neuromodulation less invasive and more therapeutic for a wider range of neurological conditions.

Our lab sits at the intersection of basic neuroscience and neuroengineering. Through experimental, clinical, and computational work, we aim to decode brain signals, and to interpret the differences beween neural information processing between default and disordered conditions. We seek to leverage this understanding to develop devices and approaches to modulate neural activity to treat neurological disorders.

Clinically Invasive Neuromodulation

Existing FDA-approved neuromodulatory interventions use electrical brain implants that modulate neural activity to alleviate symptoms. We work to understand and improve these therapies for and in human patients, with experimental efforts in living and computational model systems.

Deep Brain Stimulation Projects

Minimally Invasive Neuromodulation

We are helping to design minimally-invasive neuromodulatory approaches without requiring brain implants -- devices could be wearable, or even applied from a distance. We work with models and computation tools to help make that future a reality.

Minimally Invasive Projects

Non-Invasive Neuromodulation

Advanced neuromodulatory interventions will rely on bidirectional communication between the brain and external devices. We work to develop real-time interfacing with model and human brains to alleviate neurological symptoms.

Neural Control Projects